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Investments to fight HIV/AIDS domestically and internationally are conserving lives and turning the tide against the condition, they continue. Related StoriesResearch provides prospects for new ways of develop HIV vaccineStudy evaluates efficiency of antiretroviral treatment in HIV-infected childrenStudy: Safe areas may play critical function in community-based HIV prevention effortsColfax and Goosby highlight domestic and international HIV prevention efforts over the past two decades, discuss funding for these initiatives, and write, The actual fact of the problem is that our achievements are continuing to develop rapidly because of greater efficiencies borne of traveling our programming with evidence of impact, the growing dedication of governments and citizens in the developing world, the decreased costs of treatment, and the growing impact of prevention.