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Anti-ageing hormone called Klotho actions explained Researchers discovered an anti-aging hormone called Klotho recently. Now, a fresh study implies that this protein functions by raising the cell’s capability to detoxify dangerous reactive oxygen species. The research appears as the Paper of the Week in the November 11 problem of the Journal of Biological Chemistry, an American Society for Biochemistry and Molecular Biology journal. The klotho gene, named after the Greek goddess who spins life’s thread, is associated with preventing aging in mammals. The klotho gene product, or Klotho proteins, can be secreted in the blood and features as an anti-maturing hormone. A defect in the klotho gene in mice qualified prospects to a syndrome carefully resembling human ageing, while overexpression of the gene extends lifespan in mice.